Publicaciones (2022)
Publicaciones clasificadas por fecha descendente
Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling
Autores: David Gonzalez-Perez, Satyajit Das, Daniel Antfolk, Hadia S. Ahsan, Elliot Medina, Carolyn E. Dundes, Rayyan T. Jokhai, Emily D. Egan, Stephen C. Blacklow, Kyle M. Loh, Paulo C. Rodriguez & Vincent C. Luca
Artículo;
Nature Chemical Biology. 19, pages9–17
Fecha: sept. 2022
Doi: 10.1039/d2se01073a.
Resumen:
The Notch pathway regulates cell fate decisions and is an emerging target for regenerative and cancer therapies. Recombinant Notch ligands are attractive candidates for modulating Notch signaling; however, their intrinsically low receptor-binding affinity restricts their utility in biomedical applications. To overcome this limitation, we evolved variants of the ligand Delta-like 4 with enhanced affinity and cross-reactivity. A consensus variant [read more]
Physicochemical properties and photocatalytic activity in the 2-propanol degradation of transition metals (Zr, Zn or Nb) doped TiO2 solids
Autores: Jedidi, W; Arfaoui, J; Caudillo-Flores, U; Munoz-Batista, MJ; Ksibi, Z; Kubacka, A; Ghorbel, A; Fernandez-Garcia, M
Artículo.
Mater. Sci. Eng. B-Adv. Funct. Solid-State Mater.. vol: 286. page: 0921-5107.
Fecha: DEC. 2022.
Doi: 10.1016/j.mseb.2022.116034.
Resumen:
For improving the photocatalytic activity of titania under UV or sunlight (SL) irradiations in the gaseous phase degradation of 2-propanol, M-TiO2 catalysts were synthesized by the sol-gel method (with M = Zr, Zn and Nb) and characterized by various techniques. It was found that the solids show only the diffraction peaks of TiO2 anatase phase with high surface area and porosity. The type of transition metal affects the physicochemical properties and [read more]
Inversion of chirality in GTM-4 enantio-enriched zeolite driven by a minor change of the structure-directing agent
Autores: de la Serna, R; Arnaiz, I; Marquez-Alvarez, C; Perez-Pariente, J; Gomez-Hortiguela, L
Artículo.
Chem. Commun.. vol: 58. page: 1359-7345.
Fecha: nov-24. 2022.
Doi: 10.1039/d2cc04958a.
Resumen:
A surprising inversion of chirality of the -ITV zeolite framework is observed when the ethyl group of the enantiopure N,N-ethyl-methyl-pseudoephedrinium organic structure-directing agent is replaced by a benzyl or 2-methylbenzyl group, keeping the same molecular absolute configuration. Interestingly, chiral zeolite materials obtained with these new benzyl-containing cations reach unprecedentedly high enantiomeric excesses up to 55%..
Nitrogen-doped carbon decorated-Ni3Fe@Fe3O4 electrocatalyst with enhanced oxygen evolution reaction performance
Autores: Gebreslase, GA; Sebastian, D; Martinez-Huerta, MV; Lazaro, MJ
Artículo.
J. Electroanal. Chem.. vol: 925. page: 1572-6657.
Fecha: nov-15. 2022.
Doi: 10.1016/j.jelechem.2022.116887.
Resumen:
High performance, durable and inexpensive electrocatalyst for oxygen evolution reaction (OER) is of great importance for tenable hydrogen production via water electrolysis. Although spinel oxides (AB2O4, A, B = metal) represent a class of promising candidates for OER, their intrinsically poor electrical conductivity impacts their electrochemical performance. Herein, we employed a facile approach to transform an intrinsi-cally low active NiFe2O4 into nitrogen-doped carbon decorated Ni3Fe@Fe3O4 catalyst with improved activity and stability for alkaline OER. Initially, a pristine NiFe2O4 octahedron-like structure was synthesized by [read more]
Method for analyzing HR-TEM micrographs to propose and/or describe structures and their interaction in crystalline materials
Autores: Obeso-Estrella, R; Pawelec, B; Mota, N; Flores-Sanchez, LA; Quintana-Melgoza, JM; Yocupicio-Gaxiola, RI; Zepeda, TA
Artículo.
MethodsX. vol: 9. page: .
Fecha: . 2022.
Doi: 10.1016/j.mex.2022.101855.
Resumen:
A general and versatile method for the analysis and processing of HR-TEM data useful for several applications is presented. The first utility is to identify the structures seen in the micrographs; also can be extended to propose the interaction of structure dynamics between various phases; and also it can be hybridized with the chemical method to make a proposal of new structure and/or phase. The general method consisted of four steps: 1) micrograph pretreatment, 2) measurement of planar distances, [read more]
Aqueous phase hydrogenation of maleic acid to succinic acid mediated by formic acid: the robustness of the Pd/C catalytic system
Autores: Orozco-Saumell, A; Mariscal, R; Iglesias, J; Maireles-Torres, P; Granados, ML
Article; Early Access.
Sustain. Energ. Fuels. vol: . page: 2398-4902.
Fecha: . .
Doi: 10.1039/d2se01073a.
Resumen:
Long-term liquid phase studies of the activity in the formic acid-mediated hydrogenation of MAc to SAc were conducted in a fixed bed continuous reactor for two relevant situations: neutralising maleic and formic acids with NaOH and at the pH determined by both acids. Deactivation could only be observed when the catalyst was subjected to a WHSV of MAc above 13 g(MAc) g(cat)(-1) h(-1). Despite this deactivation, the reaction conditions can be adjusted (lowering the reaction temperature and/or decreasing the [read more]
Immobilization-stabilization of the dimeric D-amino acid oxidase from porcine kidney
Autores: Carballares, D; Fernandez-Lafuente, R; Rocha-Martin, J
Article.
Process Biochem.. vol: 122. page: 1359-5113.
Fecha: NOV. 2022.
Doi: 10.1016/j.procbio.2022.10.002.
Resumen:
This paper shows the immobilization of the dimeric D-amino acid oxidase (DAAO) following different methodologies. Immobilization on glyoxyl-agarose yielded activity recoveries under 5%, and it was discarded. The anion exchange on aminated supports permits the rapid enzyme immobilization, but its activity decreased and the final biocatalysts is less stable than the free enzyme, suggesting that the near presence of a cationic surface is negative for enzyme performance. Treating this biocatalyst with glutaraldehyde led to the full enzyme inactivation. However, immobilization at pH 7 on glutaraldehyde preactivated [read more]
Highly Active and Stable Ni/La-Doped Ceria Material for Catalytic CO2 Reduction by Reverse Water-Gas Shift Reaction
Autores: Consuelo Alvarez-Galvan, Pablo G. Lustemberg, Freddy E. Oropeza, Belén Bachiller-Baeza, Martin Dapena Ospina, María Herranz, Jesús Cebollada, Laura Collado, José M. Campos-Martin, Víctor A. de la Peña-O’Shea, José A. Alonso, and M. Verónica Ganduglia-Pirovano.
Artículo.
ACS Appl. Mater. Interfaces
Fecha: oct-03. 2022.
Doi: https://doi.org/10.1021/acsami.2c11248
Resumen:
he design of an active, effective, and economically viable catalyst for CO2 conversion into value-added products is crucial in the fight against global warming and energy demand. We have developed very efficient catalysts for reverse water-gas shift (rWGS) reaction. Specific conditions of the synthesis by combustion allow the obtention of macroporous materials based on nanosized Ni particles [read more]
Switch off/switch on of a cysteinyl protease as a way to preserve the active catalytic group by modification with a reversible covalent thiol modifier: Immobilization of ficin on vinyl-sulfone activated supports
Autores: Morellon-Sterling, R; Bolivar, JM; Fernandez-Lafuente, R
Artículo.
Int. J. Biol. Macromol.. vol: 220. page: 0141-8130.
Fecha: nov-01. 2022.
Doi: 10.1016/j.ijbiomac.2022.08.155.
Resumen:
The immobilization of ficin (a cysteinyl proteases) on vinyl sulfone agarose produced its almost full inactivation. It was observed that the incubation of the free and immobilized enzyme in beta-mercaptoethanol produced a 20 % of enzyme activity recovery, suggesting that the inactivation due to the immobilization could be a consequence of the modification of the catalytic Cys. To prevent the enzyme inactivation during the immobilization, switching off of ficin via Cys reaction with dipyridyl-disulfide was implemented, giving a reversible disulfide bond that produced a [read more]
Sulfur-doped carbon nanofibers as support for tantalum oxides bifunctional catalysts for the oxygen reduction and evolution reactions
Autores: Ruiz-Cornejo, JC; Sebastian, D; Pardo, JI; Martinez-Huerta, MV; Lazaro, MJ
Artículo.
J. Power Sources. vol: 546. page: 0378-7753.
Fecha: oct-30. 2022.
Doi: 10.1016/j.jpowsour.2022.231988.
Resumen:
Highly efficient, low-cost and stable bifunctional catalysts for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are highly desirable for the development of green electrochemical energy storage and conversion devices. Here, we report the synthesis of sulfur-doped carbon nanofibers (CNF) as support for tantalum oxide nanoparticles. Carbon nanofibers and tantalum oxides represent a durable choice for oxygen electrocatalysis, but an improvement of catalytic activity is required. Upon doping, sulfur is found to be mainly bonded to carbon as C-S-C species [read more]
Surface modification of Cu2O-CuO photocatalyst on Cu wire through decorating with TiO(2 )nanoparticles for enhanced visible light photocatalytic activity
Autores: Ansari, F; Sheibani, S; Fernandez-Garcia, M
Artículo.
J. Alloy. Compd.. vol: 919. page: 0925-8388.
Fecha: oct-25. 2022.
Doi: 10.1016/j.jallcom.2022.165864.
Resumen:
In this paper, the fabrication of Cu2O-CuO/TiO2 nanocomposite photocatalysts on Cu wire was performed successfully via chemical-thermal oxidation and sol-gel process. The chemical-thermal oxidations were applied for Cu2O-CuO nanostructure fabrication on the Cu wire surface. The sol-gel process was utilized for TiO2 nanoparticles decoration as a surface modification process for photocatalytic activity improvement. The X-ray diffraction analysis (XRD), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS) showed the coexistence of multiple components including Cu2O, CuO, Cu, and TiO2 in the nanocomposite. Field emission electron scanning microscopy [read more]
Surface modification of Cu2O-CuO photocatalyst on Cu wire through decorating with TiO2 nanoparticles for enhanced visible light photocatalytic activity
Autores: Ansari, F; Sheibani, S; Fernandez-Garcia, M
Article.
J. Alloy. Compd.. vol: 919. page: 0925-8388.
Fecha: oct-25. 2022.
Doi: 10.1016/j.jallcom.2022.165864.
Resumen:
In this paper, the fabrication of Cu2O-CuO/TiO2 nanocomposite photocatalysts on Cu wire was performed successfully via chemical-thermal oxidation and sol-gel process. The chemical-thermal oxidations were applied for Cu2O-CuO nanostructure fabrication on the Cu wire surface. The sol-gel process was utilized for TiO2 nanoparticles decoration as a surface modification process for photocatalytic activity improvement. The X-ray diffraction analysis (XRD), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS) showed the coexistence of multiple components including Cu2O, CuO, Cu, and TiO2 in the nanocomposite. Field emission electron scanning microscopy [read more]
Preface to the JPCM special issue on physical and chemical properties of reducible oxides
Autores: Luches, P; Ganduglia-Pirovano, MV
Editorial Material.
J. Phys.-Condes. Matter. vol: 34. page: 0953-8984.
Fecha: oct-19. 2022.
Doi: 10.1088/1361-648X/ac877f.
Resumen:
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Characterization of lignin and lignin-derivatives from biomass. Application as expander of Lead-acid battery
Autores: Naim, MT; Lara-Serrano, M; Romero, AF; Morales-delaRosa, S; Campos-Martin, JM; Moreno, JRA; Ocon, P
Artículo.
Arab. J. Chem.. vol: 15. page: 1878-5352.
Fecha: OCT. 2022.
Doi: 10.1016/j.arabjc.2022.104127.
Resumen:
Expanders, as lignosulfonates, are crucial for a good performance of Pb/acid batteries. In the process of discharge, the Pb and the PbO2 go to PbSO4. The formed PbSO4 is adsorbed on the surface of the Pb electrode and dramatically reduces the lifetime of the battery by the formation of big PbSO4 crystals. In order to prevent that, the addition of expanders in the negative electrode is an economic solution to prevent the formation of big crystals. In [read more]
Optimization of the immobilization of xylanase from Thermomyces lanuginosus to produce xylooligosaccharides in a batch type reactor
Autores: Alagoz, D; Varan, NE; Yildirim, D; Fernandez-Lafuente, R
Article.
Mol. Catal.. vol: 531. page: 2468-8231.
Fecha: OCT. 2022.
Doi: 10.1016/j.mcat.2022.112647.
Resumen:
The xylanase from Thermomyces lanuginosus was immobilized following very different protocols, using 3-aminopropyl (Xyl/CNT-NH2) and carboxylic acid (Xyl/CNT-C) functionalized multi-walled carbon nanotubes or after glutaraldehyde activation of CNT-NH2 (Xyl/CNT-Glu). It was also immobilized on carboxylic acid functionalized multi-walled carbon nanotubes via carbodiimide chemistry (Xyl/CNT-COOH). The free and all the immobilized xylanase derivatives showed maximal catalytic activity at pH 7.5 and at 65 ?. Xyl/CNT-Glu showed 24.0-fold higher thermal stability than the free xylanase at 70 ?. The immobilized xylanase derivatives were used for the [read more]
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