Authors: Perez-Rizquez, C; Abian, O; Palomo, JM

Chem. Commun.. vol: 55. page: 1359-7345.
Date: nov-07. 2019.
Doi: 10.1039/c9cc06971b.

Herein we report for the first time the site-selective C-H bond arylation of tryptophan and tryptophan residues in proteins in aqueous media at room temperature by using a PdNP bionanohybrid as a heterogeneous catalyst. The reaction proceeds using a stable aryldiazonium salt without a base..