Structural Insights into the Substrate Promiscuity of a Laboratory-Evolved Peroxygenase

Authors: Ramirez-Escudero, M; Molina-Espeja, P; de Santos, PG; Hofrichter, M; Sanz-Aparicio, J; Alcalde, M

ACS Chem. Biol.. vol: 13. page: 1554-8929.
Date: DEC. 2018.
Doi: 10.1021/acschembio.8b00500.

Because of their minimal requirements, substrate promiscuity and product selectivity, fungal peroxygenases are now considered to be the jewel in the crown of C-H oxyfunctionalization biocatalysts. In this work, the crystal structure of the [read more]