The  Bioelectrocatalysis Group of the ICP was started by Prof. Victor M. Fernández in the mid 80s. Since then the main research goals of the group have been the study and characterization of redox enzymes and their interfaces with electroactive surfaces, as well as the applications of bioelectrodes.

Research lines

  • Structure/function relationship studies of redox metalloenzymes
  • Development of strategies for oriented and stable immobilization of redox enzymes on electrodes for applications in biofuel cells, biosensors, hydrogen production or cofactor regeneration.
  • Development and characterization of nano-structured electrodes and the study of the integration of nano-materials (gold/magnetic nanoparticles, carbon nanotubes, graphene) with biocatalysts.
  • Development of photocatalysts and photoelectrocatalysts based on redox enzymes immobilized on inorganic semiconductors.
  • Reconstitution of membrane enzymes on electrodes modified with biomimetic membranes.


Jefa/e del Grupo

Antonio López de Lacey (Investigador Científico)

Personal del Grupo

Marcos Pita Martínez (Científico Titular)

José María Abad Pastor (Científico Titular)

Maryam Saket Osgouei (Postdoctoral Marie Curie)

Gabriel García Molina (Postdoctoral)

Gabriel Luna López (Predoctoral)

Carina Felix Figueiredo (Predoctoral)

Christian M. Fera (Predoctoral)

Bioelectrocatalisis grupo


  • PID2021-124116OB-I00. “Electrocatalytic and photoelectrocatalytic inorganic/ enzymatic systems for Selective CO2 Reduction and NH3 Production (ELECTROSYSCAT)”. Entity: Ministerio de Ciencia e Innovación.
    Proyecto PID2021-124116OB-I00 financiado por MCIN/AEI/10,13039/501100011033 y por la Unión Europea NextGenerationEU/PRTR. 
  • 2021 Ecologic Digital Transition call. TED2021-129694B-C22. “Development of electrolyzers for their integration in a system that uses photovoltaics to power the electrochemical conversion of CO2 into methanol and ethylene (DEFY-CO2)”.
    Proyecto TED2021-129694B-C22 financiado por MCIN/AEI/10,13039/501100011033 y por la Unión Europea NextGenerationEU/PRTR. 
  • Y2020/EMT-6419 CEOTRES-CM. Generación Fotovoltaica de Combustibles Solares. Entity: Proyectos Sinérgicos I+D de la Comunidad de Madrid.
  • MSCA-ITN-2018. ImplantSens. “Mass-transfer independent long-term implantable biosensors”. Entity: European Research Council, Marie Sklodowska-Curie Actions, H2020-MSCAITN-2018-813006.


  • José M. Abad, Marcos Pita, Antonio L. De Lacey. “Single Electron Charging of Thioctic Acid Monolayer-Protected Au Clusters”. Journal of Physical Chemistry Letters, 2023, 14, 1452-1456. DOI: 10.1021/acs.jpclett.2c03940.
  • Gabriel García-Molina, Paolo Natale, Ana M. Coito, Daniel G. Cava, Inés A. C. Pereira, Iván López-Montero, Marisela Vélez, Marcos Pita, Antonio L. De Lacey. Electro-enzymatic ATP regeneration coupled to biocatalytic phosphorylation reaction”. Bioelectrochemistry, 2023, 152, 108432. DOI: 1016/j.bioelechem.2023.108432.
  • Gabriel Luna-Lopez, Melisa del Barrio, Jennifer Fize, Vincent Artero, Ana Margarida Coito, Inês A. C. Pereira, José Carlos Conesa, Ana Iglesias-Juez, Antonio L. De Lacey, Marcos Pita*. “Photobio-electrocatalytic production of H2 Using Fluorine-doped Tin Oxide (FTO) Electrodes Covered with a NiO-In2S3 p-n Junction and NiFeSe Hydrogenase”. Bioelectrochemistry 2023, 150, 108361. DOI: 10.1016/j.bioelechem.2022.108361.
  • Melisa del Barrio, Emiliano Martínez-Periñán, Cristina Gutiérrez-Sánchez, Marcos Pita, Antonio L. de Lacey, Félix Pariente, Encarnación Lorenzo. “Cholesterol biosensor based on a peroxide-free biofuel cell built on carbon nanodots enhanced-electrodes”. Sensors & Actuators B. Chemical, 2023, 375, 132895 DOI: 1016/j.snb.2022.132895.
  • Melisa del Barrio*, Moumita Rana, Juan José Vilatela, Encarnación Lorenzo, Antonio L. De Lacey, Marcos Pita*. “Photoelectrocatalytic detection of NADH on n-type silicon semiconductors facilitated by carbón nanotube fibers”. Electrochimica Acta 2021, 377, 138071.
  • Julia Álvarez-Malmagro, Ana R. Oliveira, Cristina Gutierrez-Sanchez, Beatriz Villajos, Inês A. C. Pereira, Marisela Vélez, Marcos Pita, Antonio L. De Lacey. “Bioelectrocatalytic Activity of W-Formate Dehydrogenase Covalently Immobilized on Functionalized Gold and Graphite Electrodes.” ACS Applied Materials and Interfaces 2021, 13, 11891-11900. DOI: 10.1021/acsami.0c21932.
  • Melisa del Barrio, Gabriel Luna-López, Marcos Pita*. “Enhancement of Biosensor by Implementing Photoelectrochemical Processes.” Sensors 2020, 20 (11), 1-21. DOI: 10.3390/s20113281.
  • Gabriel García-Molina, Paolo Natale, Laura Valenzuela, Julia Alvarez-Malmagro, Cristina Gutierrez-Sanchez, Ana Iglesias-Juez, Iván López-Montero, Marisela Velez, Marcos Pita*, Antonio L. De Lacey*. “Potentiometric Detection of ATP Based on the Transmembrane Proton Gradient Generated by ATPase Reconstituted on a Gold Electrode.” Bioelectrochemistry 2020, 133, 107490. DOI: 10.1016/j.bioelechem.2020.107490.
  • Julian Szczesny, Adrian Ruff, Ana R. Oliveira, Marcos Pita, Inês A. C. Pereira, Antonio L. De Lacey, Wolfgang Schuhmann. “Electroenzymatic CO2 Fixation Using Redox Polymer/Enzyme-Modified Gas Diffusion Electrodes.” ACS Energy Letters 2020, 5, 321-327. DOI: 10.1021/acsenergylett.9b02436.