Optimization of biocatalysts and bioprocesses

Optimization of biocatalysts and bioprocesses2019-10-01T17:55:27+02:00


“Optimization of enzymatic biocatalysts and bioprocess” research group is  a one of recent creation (2009). After working since 1988 in several areas of biocatalysis, under the supervision of Dr Guisan, and a postdoctoral stand in UCL under supervision of Dr Cowan (1993-1996) the leader research has a wide experience in the study of the interactions between biomacromolecules and activated solids, both to purify or immobilize/stabilize these biomacromolecules. Moreover, he has expertise in the chemical and physical modification of these biomacromolecules, both to improve their properties or to improve their immobilization performance. He has also experience on the integration of other technological tools to have a better biocatalyst, like microbiology (using enzymes from thermophiles) molecular biology (purification by affinity, directed immobilization/rigidification)

With these biocatalysts, many different reactions have been studied, e.g. selective hydrolysis, amidations and esterifications (thermodynamically or kinetically controlled) racemic mixtures resolution, regio and enantio selective oxidations and reductions
Currently, founded on the possibility of the availability of very stable, selective and active biocatalysts, and by collaborations with other researchers (from ICP and other centres), we have started new research lines in combo-catalysis and production of catalytic aptamers.

Our group has close relation with several nacional researchers from other institutions, as Prof Pedro Lozano (Universidad de Murcia), expert in biocatalysis in new no conventional emdia (ionic liquids, supercritical fluids) and Dr Eduardo García-Verdugo (Unversidad Jaume I), expert in green chemistry (http://www.quimicasostenible.uji.es/)..

Among the international collaborations, we want to remark that with the gropups leadinig by  Drs Rodrigo Torres y  Claudia Ortiz, ( Universidad Industrial de Santander,(Bucaramanga, Colombia) (http://ciencias.uis.edu.co/gibim/) and the collaboration with  l Dr Rafael C. Rodrigues, de la Universidade Federal do Rio Grande do Sul, (Porto Alegre, Brasil). In both cases, the  intesnsity of visits, cosupervision of thesis and joint participation in projects show the high integration between our reserah groups.

Since end of 2014, he is member of the scientific advisory board of the Canadian company  CO2 solutions (http://www.co2solutions.com/en/scientific-advisory-board)

Case studies

El investigador responsable del grupo pertenece a los sigueinetes comites editoriales

1.- Miembro del equipo editorial de las siguientes revistas:

I.- Editor asociado de la revista Process Biochemistry Diciembre 2011-

II.- Editor ejecutivo
Advances in Bioscience and Biotechnology (Diciembre-2011-)

III.- Miembro del comite editorial:

A.- Enzyme and Microbial Technology (julio 2005) .
B.- Journal of Molecular Catalysis B: Enzymatic (2008)
C.- The Open Organic Chemistry Journal  (noviembre 2007)
D.- Anti-Infective Agents in Medicinal Chemistry (noviembre 2007)
E.- The Open Enzyme Inhibition Journal (Febrero 2008-)
F.- The Open Food Science Journal (Julio 2008-)
G.- Enzyme Research (2009-)
H.- Advances in Bioscience and Biotechnology (2011)
I.- Membrane Science & Technology-Open Acces (2011-)
J.- International Journal of Organic Chemistry (2011-2012)
K.- Current catalysis (2011-)
L.- Journal of Enzyme Research (2010-)
M.- Advances in Chemical Engineering and Science (2011-)
N- Green and Sustainable Chemistry (2011-)
Ñ.- Peer J (2012-)2015
O- Molecules
P-Journal of Biotechnology


Fernández Lafuente, Roberto – Group leader




May 2023
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